The invention concerns amide derivatives of Formula (Ia) wherein X is —NHCO—
or —CONH—; m is 0-3; R1 is a group such as hydroxy, halogeno,
trifluoromethyl, cyano, mercapto, nitro, amino, carboxy and carbamoyl; n is 0-2;
R2 is a group such as hydroxy, halogeno, trifluoromethyl, cyano, mercapto,
nitro, amino and carboxy; R3 is hydrogen, halogeno, (1-6C)alkyl or (1-6C)alkoxy.
q is 0-4; and Q is a group such as aryl, aryloxy, aryl—(1-6C)alkoxy, arylamino
and N—(1-6C)alkyl-arylamino; or pharmaceutically-acceptable salts or in-vivo-cleavable
caters thereof; processes for their preparation, pharmaceutical compositions containing
them and their use in the treatment of diseases or medical conditions mediated
by cytokines.