A process is provided for making (-)-epigallocatechin gallate (EGCG) by subjecting
a green tea extract to chromatography on a macroporous polar resin, eluting EGCG
from the resin with a polar elution solvent, optionally concentrating the eluate,
optionally regenerating the resin by desorbing the remaining catechins, and optionally
concentrating the desorbed catechins.