The system can be used for the automatic analysis of images, including a matrix of spots, such as images of DNA microarrays after hybridization. The system can be associated—and preferably integrated in a single monolithic component implementing VLSI CMOS technology—to a sensor for acquiring the images. The system includes a circuit for processing the signals corresponding to the images, configured according to a cellular neural network (CNN) architecture for the parallel analogue processing of signals.