The present invention relates to the delivery of anti-migraine compounds through
an inhalation route. Specifically, it relates to aerosols containing sumatriptan,
frovatriptan, or naratriptan that are used in inhalation therapy. In a method aspect
of the present invention, one of sumatriptan, frovatriptan, or naratriptan is administered
to a patient through an inhalation route. The method comprises: a) heating a composition,
comprising sumatriptan, frovatriptan, or naratriptan, to form a vapor; and, b)
allowing the vapor to cool, thereby forming a condensation aerosol with less than
5% of the drug degradation products. In a kit aspect of the present invention,
a kit for delivering sumatriptan, frovatriptan, or naratriptan through an inhalation
route is provided which comprises: a) a thin coating of a sumatriptan, frovatriptan,
or naratriptan composition; and, b) a device for dispending said thin coating as
a condensation aerosol.