Modifications of the peptide pyrrhocoricin permit the production of a variety of anti-bacterial or anti-fungal peptides having general formula R1-Asp-Lys-Gly-X-Y-Leu-Pro-Arg-Pro-Thr-Pro-Pro-Arg-Pro-Ile-Tyr-X-Y-R2 SEQ ID NO: 1 or multimeric compositions containing more than a single peptide of that formula. These peptides may be straight chain or cyclic peptides, and may contain one or more non-cleavable bonds. These peptides are characterized by anti-bacterial or anti-fungal activity and metabolic stability in mammalian serum. These peptides are useful in anti-bacterial or anti-fungal pharmaceutical compositions and for further drug development or identification of other antibiotic or anti-fungal compounds.


< Mouse model for hepatitis C

< Tendon-inducing compositions

> 1-O-L-arginyl ester 3-O-monoacyl glycerides and 1-O-L-arginyl ester 2,3-O-diacyl glycerides type surface active agents

> Compositions containing recombinant poxviruses having foreign DNA expressed under the control of poxvirus regulatory sequences

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