The present invention relates to a compound of the formula
##STR1##
wherein R1 is substituted aryl, heteroaryl and the like, R2
and R3 are hydrogen, alkyl, halogen, hydroxyl group and the like,
Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like,
X is halogen, cyano, nitro, amino and the like, X is hydrogen, halogen,
cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and
a salt thereof, and a medicine containing the said compound. The compound of the
present invention shows a superior inhibitory effect on activated lymphocytes proliferation
and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.
