A combination handheld package sealer/wireless scanning/imaging device is provided, having a housing (with a handle thereon), a sealer coupled therewith, and a wireless scanning/imaging device coupled therewith. A user of the device herein may simultaneously seal a package, record package identification and condition data, and transmit said data to a central station via a communication network. Further, a method of preparing a package for shipment using the combination handheld adhesive applicator/wireless scanning/imaging device is provided, as well as a system incorporating same, and a computer program product embodied therein and on a central station for storing and analyzing the data recorded using the device.