A highly fire-resistant and environmentally-friendly panel of 2 mm to 28 mm may be manufactured by a blending of magnesium compounds, sodium silicate, kaolin, fillers, and additives to form the core materials, reinforced by 4 layers of fire-resistant glass fiber meshes and fabrics. Using a proprietary ITC process that accelerates the chemical reactions of the ingredients to generate sufficient heat without external supply of energy, the panels may be completely cured within 24 hours instead of 10 days. The use of waste materials, energy-saving curing system and no gas emission manufacturing process combined to make this panel an eco-friendly product which offers the world's highest-rated fire resistance of 5 hours, high flexural strength, low density, durability and effective water-resistance.