Method and apparatus for detecting biomolecular interactions. The use of labels
is not required and the methods may be performed in a high-throughput manner. An
instrument system for detecting a biochemical interaction on a biosensor. The system
includes an array of detection locations comprises a light source for generating
collimated white light. A beam splitter directs the collimated white light towards
a surface of a sensor corresponding to the detector locations. A detection system
includes an imaging spectrometer receiving the reflected light and generating an
image of the reflected light.