Novel compounds of formula (I) to (VI), which more particularly include sulfonylurea
derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine
derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives which
are effective platelet ADP receptor inhibitors. These derivatives may be used in
various pharmaceutical compositions, and are particularly effective for the prevention
and/or treatment of cardiovascular diseases, particularly those diseases related
to thrombosis. The invention also relates to a method for preventing or treating
thrombosis in a mammal comprising the step of administering a therapeutically effective
amount of a compound of formulae (I)-(VI), or a pharmaceutically acceptable salt thereof.