Compositions including an aromatic compound for inhibiting the production
of exoproteins by Gram positive bacteria are disclosed. The aromatic inhibitory
compounds of the present invention have the general formula:
##STR1##
wherein R1 is selected from the group consisting of H,
##STR2##
—OR5, —R6C(O)H, —R6OH,
—R6COOH, —OR6OH, —OR6COOH, —C(O)NH2,
##STR3##
and NH2 and salts thereof; R5 is a monovalent saturated
or unsaturated aliphatic hydrocarbyl moiety; R6 is a divalent saturated
or unsaturated aliphatic hydrocarbyl moiety; R7 is a trivalent saturated
or unsaturated aliphatic hydrocarbyl moiety; R8 is a monovalent substituted
or unsubstituted saturated or unsaturated aliphatic hydrocarbyl moiety which may
or may not be interrupted with hetero atoms; R2, R3, and
R4 are independently selected from the group consisting of H, OH, COOH,
and —C(O)R9; R9 is hydrogen or a monovalent saturated
or unsaturated aliphatic hydrocarbyl moiety.