A sealing structure for providing a seal between panels composing a roof panel with excellent sealing properties and good appearance therearound. The roof panel includes at least one sliding panel and non-sliding panels arranged adjacent to the sliding panel in a longitudinal direction of a vehicle roof, and a weather strip is attached to provide a seal between the sliding panel and the non-sliding panels. The weather strip has a base portion for attachment to a frame member, and a tubular seal portion formed integrally with the base portion on the upper side thereof. The tubular seal portion has a bridge part in an interior space thereof to support the tubular seal portion against the sliding panel which is in its closed position.