The present invention relates to novel fatty acid analogues of the general formula
(I): CH3—[CH2]m—[xi—CH2]n—COOR,
wherein n is an integer from 1 to 12, and wherein m is an integer from 0 to 23,
and wherein i is an odd number which indicates the position relative to COOR, and
wherein Xi independent of each other are selected from the group comprising
O, S, SO, SO2, Se and CH2, and wherein R represents hydrogen
or C1-C4 alkyl, with the proviso that at least one of the
Xi is not CH2, or a salt, prodrug or complex thereof, for
the preparation of a pharmaceutical composition for the treatment and/or prevention
of primary and/or secondary stenosis. Further the present invention relates to
the use of said compounds for the prevention and/or treatment of a disease caused
by procedural vascular trauma and/or pathological proliferation of smooth muscle
cells, and/or an increased level of plasma homocysteine.
