A formulation for male contraception comprising a progestin possessing both estrogenic
and androgenic properties is remarkably effective for spermatogenesis suppression
in males. The progestin Norethisterone (NET), particularly its derivatives Norethisterone
acetate and Norethisterone enanthate in sufficient doses induce oligozoospermia
or azoospermia in males. Formulations further comprising an androgen, such as a
testosterone derivative such as a testosterone ester, particularly testosterone
undecanoate, are especially effective male contraceptive formulations.