A system for pressure ulcer prophylaxis and treatment includes an annunciator which is attached to the outer face of the door or to the doorway of a patient's room and a bedside patient position sequence indicator. The annunciator includes a timing device with settable cycle duration and provides both visual and audible signals to indicate that a prescribed patient turning regimen cycle now requires repositioning of the patient. The annunciator generates a first signal when the cycle duration enters an expiry window and generates a different, intensified signal after the cycle has ended without being reset by a caregiver. The patient position sequence indicator includes a visual display which advises a caregiver of the position in which the patient was last placed and the next sequential position to which the patient is to be moved.