The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs that are non-acidic or segregating the metoclopramide and NSAID, the storage life of the compositions has been increased. Also disclosed are coordinated dosage forms for the sequential release of drugs. The invention encompasses methods of treating migraine using any of these dosage forms.

 
Web www.patentalert.com

< Combinations comprising an antidiarrheal agent and an epothilone or an epothilone derivative

< Emulsion vehicle for poorly soluble drugs

> Anti-mesothelin antibodies having high binding affinity

> Water-in-oil emulsions with ethylene oxide groups, compositions, and methods

~ 00253