This invention relates to novel cyclopropyl -amino acids derivatives
of the formula
##STR1##
wherein R1 through R4 are defined as in the specification,
pharmaceutical compositions containing them and their use for the treatment of
various central nervous system and other disorders. The cyclopropyl -amino
acids derivatives of this invention exhibit activity as alpha2delta ligands (2
ligands). Such compounds have affinity for the 2 subunit of a calcium channel.
