Vectors for producing polypeptides heterologous to prokaryotes are described
comprising, along with the polypeptide-encoding nucleic acid, anti-termination
nucleic acid that inhibits intragenic transcription termination with a non-lambda
promoter therefor and/or nucleic acid encoding a GreA or GreB protein and a promoter
therefor. Also described are processes for producing a heterologous polypeptide
in prokaryotic host cells utilizing such elements to improve the quality and/or
quantity of heterologous polypeptide produced.