Multi-layer substrates for a premoistened wipe capable of controlled fluid release comprise a reservoir layer and a surface contact layer, wherein the reservoir and surface contact layers have certain blends of hydrophilic and hydrophobic fibers, as well as certain basis weights. Premoistened wipes for treating and/or cleaning a surface comprise the multi-layer substrate and a liquid composition impregnated into the multi-layer substrate, wherein the liquid composition comprises a surfactant system and/or a solvent system. Methods of treating and/or cleaning a surface comprise the step of contacting the surface with a premoistened wipe of the present invention.