A composition for nasal administration comprising varenicline or its
pharmaceutically acceptable salt and at least one excipient. The
invention also provides a composition for buccal administration
comprising varenicline or its pharmaceutically acceptable salt and at
least one excipient to form a solid dosage form, wherein the solid dosage
form disintegrates in an oral cavity at body temperature and may adhere
to body tissue of the oral cavity; a composition for pulmonary
administration comprising varenicline or its pharmaceutically acceptable
salt and at least one excipient; and, a method for reducing nicotine
addiction, aiding in the cessation of, or lessening of tobacco use in a
subject.