A data-driven, hierarchical information navigation system and method enable search of sets of documents or other materials by certain common attributes that characterize the materials. The invention includes several aspects of a data-driven, hierarchical navigation system that employs this navigation mode. The navigation system of the present invention includes features of an interface, a knowledge base and a taxonomy definition process and a classification process for generating the knowledge base, a graph-based navigable data structure and method for generating the data structure, World Wide Web-based applications of the system, and methods of implementing the system. Users are able to search or browse a particular collection of documents by selecting desired values for the attributes. A data-driven, hierarchical information navigation system and method enable this navigation mode by associating terms with the materials, defining a set of hierarchical relationships among the terms, and providing a guided search mechanism based on the relationship between the terms.