Novel azetidinyl and pyrrolidinyl compounds are ligands of melanocortin-4 receptors and are useful for treating conditions responsive to the modulation of melanocortin-4 receptors such as obesity, diabetes, and sexual dysfunction. ##STR1##

 
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> 1,2,4-thiadiazole derivatives as melanocortin receptor modulators

> 3-azabicyclo[3.1.0]hexane derivatives
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