A system for inserting at least a portion of an insertion set through the
surface of a tissue, having: an inserter with a moveable plunger disposed
within a cavity therein; an insertion set holder received into the distal
end of the cavity; and an insertion set received into the insertion set
holder, wherein the insertion set is moveable within the insertion set
holder such that when the plunger is advanced into contact with the
insertion set, the insertion set advances through the insertion set
holder to a position at which at least a portion of the insertion set
extends out of the distal end of the cavity.