A compound represented by formula (I); a process for producing a compound
(substance F-1490) of formula (I), wherein X represents --O-- and R
represents a hydroxyl group, by using a microorganism belonging to the
genus Cunninghamella; and a Cunninghamella sp. F-1490 strain (FERM
BP-8287) capable of producing the substance F-1490; and an osteoclast
differentiation inhibitory agent containing as an active ingredient the
compound represented by formula (I): ##STR00001## wherein X represents
--O-- or --CH.sub.2--, and R represents a hydroxyl group when X
represents --O--, or a hydrogen atom when X represents --CH.sub.2--.