The present invention relates to 5-aminomethylpyrazolo[4,3-d]pyrimidines of the general formula (I) ##STR00001## in which the radicals R.sup.1 to R.sup.6 have the meaning indicated in the text. The compounds show phosphodiesterase V inhibition and can be employed for the treatment of conditions of the cardiovascular system and for the treatment of potency disorders.