In accordance with the present invention, stable electroosmotic flow
systems and methods for designing the same are disclosed. The invention
provides electroosmotic flow systems comprising electroosmotic flow
elements, including bridge elements, that have matching flux ratios,
i.e., when two or more elements of an electroosmotic flow system are in
fluidic and electrical communication at a junction, the flux ratio for
each of the elements is selected so that the difference in flux ratios of
any two elements is less than a target value. The invention also provides
methods for designing such systems. Also disclosed is a novel design for
the terminal portions of electroosmotic flow (EOF) and bridge elements
and for junctions in electroosmotic flow systems, whereby the elements
are designed so that the terminal current flux is much smaller than the
element current flux.