The present invention provides pyrazole derivatives represented by the
general formula: wherein R.sup.1 represents H, an optionally substituted
C.sub.1-6 alkyl group etc.; one of Q and T represents a group selected
from the following groups: and the other represents
--(CH.sub.2).sub.n--Ar wherein Ar represents an optionally substituted
C.sub.6-10 aryl group or an optionally substituted C.sub.1-9 heteroaryl
group; and n represents an integral number from 0 to 2, an optionally
substituted C.sub.1-6 alkoxyl group, an optionally substituted amino
group, an optionally substituted C.sub.2-9 heterocycloalkyl group or an
optionally substituted heterocycle-fused phenyl group; R represents an
optionally substituted C.sub.3-8 cycloalkyl group, an optionally
substituted C.sub.6-10 aryl group etc., pharmaceutically acceptable salts
thereof or prodrugs thereof, which exhibit an excellent inhibitory
activity in human 1,5-anhydroglucitol/fructose/mannose transporter and
are useful as agents for the prevention, inhibition of progression or
treatment of a disease associated with the excess uptake of at least a
kind of carbohydrates selected from glucose, fructose and mannose or a
disease associated with hyperglycemia (e.g., diabetic complications,
diabetes, etc.), and pharmaceutical compositions comprising the same,
pharmaceutical uses thereof, and intermediates for production thereof.