An airway adapter suitable for use with patients having low tidal volumes, e.g., neonates, which minimizes deadspace in the airway and promotes smooth flow of gases through the adapter. The adapter includes a first portion adapted to couple to a tubular adapter, such as an endotracheal tube adapter, and a second portion adapted to couple to a ventilation tube. A longitudinally compressible member is coupled to the first portion to minimize deadspace in the adapter. A portion of the compressible member resiliently contacts and seals against a tubular adapter upon assembly of the airway adapter therewith.