The invention relates to derivatives corresponding to formula I:
##STR00001## in which X is an alkyl-(CH.sub.2).sub.n-- chain with n=0,
1 or 2, or O or N, Z is an aromatic which may contain heteroatoms chosen
from O, N or S, as substitutions for the carbon atoms constituting said
aromatic ring, this ring being substituted or otherwise with Rb, Rb
represents 1 to 3 substituents chosen from --OH, --OR, --COOH, --COOR,
--COH, --COR, --NH.sub.2, --NH(R), --NH(R,R'), --SH, --SR and CN, Ra is H
or --(CH.sub.2).sub.n'--Y, with n'=0, 1, 2 or 3 and Y and --CH.sub.3,
--COOH, --COOR, --CN, --OH, --OR, SR, or an aryl group optionally
substituted with Rb, R and R' represent a linear or branched alkyl chain
of 1 to 4 C, and their pharmaceutically acceptable salts. Application as
active ingredient of medicaments inhibiting retrovirus integrases.