An artificial insemination system and its use requires a sheath which has a first lumen for receiving and holding an endoscope, and a second lumen through which semen can be injected into the uterus of the animal to be inseminated. Additionally, the sheath includes a blunt guide probe which extends distally from the distal end of the sheath. A window covers the distal end of the first lumen so that the user can use the endoscope to view the guide probe and the general area surrounding the guide probe. When using the system, the endoscope is initially inserted into the first lumen of the sheath. The combination of sheath and endoscope are then inserted into the vagina of the animal and, using the endoscope, the guide probe is position at the cervical os. While continuing to view the guide probe with the endoscope, the guide probe is directed through the cervix until the distal end of the second lumen is positioned in the uterus. Next, an injector filled with semen is connected in fluid communication with the proximal end of the second lumen and the semen is injected into the uterus through the second lumen. The entire system is then withdrawn and the sheath can be discarded is desired.