The invention relates to 4-cyanopyrazole-3-carboxamide derivatives of
formula (I): in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5,
R.sub.6, R.sub.7, R.sub.8 are as described herein. Also disclosed and
claimed are the method of preparation and therapeutic application of
compound of formula (I).