A soybean cultivar, designated SE73753, is disclosed. The invention relates to the seeds of soybean cultivar SE73753, to the plants of soybean SE73753 and to methods for producing a soybean plant produced by crossing the cultivar SE73753 with itself or another soybean variety. The invention further relates to hybrid soybean seeds and plants produced by crossing the cultivar SE73753 with another soybean cultivar.