The present invention relates to the delivery of antihistamines through an
inhalation route. Specifically, it relates to aerosols containing
antihistamines that are used in inhalation therapy. In a method aspect of
the present invention, an antihistamine is delivered to a patient through
an inhalation route. The method comprises: a) heating a thin layer of an
antihistamine, on a solid support, to form a vapor; and, b) passing air
through the heated vapor to produce aerosol particles having less than 5%
antihistamine drug degradation products. In a kit aspect of the present
invention, a kit for delivering an antihistamine through an inhalation
route is provided which comprises: a) a thin layer of an antihistamine
drug and b) a device for dispensing said thin layer as a condensation
aerosol.