The administration of antiestrogens to men suffering a relative androgen
deficiency stimulates the body's production of testosterone leading to a
correction of the deficiency. For example, male menopause, loss of
cognitive function, insulin resistance, type 2 diabetes, obesity,
excessive weight, Alzheimer's disease, and combinations thereof, can all
be characterized by significant decreases in serum levels of bioavailable
androgens. Administration of antiestrogens to men restores optimum serum
levels of bioavailable androgens, and, thus, serves as a treatment for
these disorders and relative androgen deficiency in general.