The present invention relates to compounds comprising the following
formula: R.sup.0-Q-X-Q'-W-U-V-G-M (I) These compounds are useful as
pharmacologically active compounds. They exhibit an antithrombotic effect
and are suitable, for example, for the therapy and prophylaxis of
cardiovascular disorders such as thromboembolic diseases or restenoses.
These compounds are reversible inhibitors of the blood clotting enzymes
factor Xa (FXa) and/or factor VIIa (FVIIa), and can generally be used to
treat, prevent, or cure conditions in which an undesired activity of
factor Xa and/or factor VIIa is present, or where inhibition of factor Xa
and/or factor VIIa is intended. The invention further relates to
processes for the preparation of these compounds, methods of their use
(e.g., as active ingredients in pharmaceuticals), and pharmaceutical
preparations comprising them.