Computer systems and methods facilitate exploring results of drug
candidate modeling. In one embodiment, the software is configured to
receive raw data simulated by a probabilistic model of clinical safety,
tolerability, and efficacy of a drug candidate. Index information is
extracted from the raw data and then referenced to generate a metadata
file, the structure of the metadata file,explicitly reflecting a
hierarchical structure of the model. The metadata file is in turn used to
convert the raw data into a binary file, the metadata file explicitly
identifying locations within the binary file, of treatment scenario
information types and output performance information types. The metadata
file is also referenced to generate an interface configured to receive
inputs from a non-expert audience, and in turn present relevant subsets
of the binary file in a limited number of plot and tabular formats. By
standardizing presentation and manipulation of data from different
models, software and methods in accordance with the present invention
facilitate meaningful interaction between a non-expert audience, and the
complex abstract mathematical models predicting drug behavior. The
heightened audience-model interaction afforded by the present invention
in turn promotes uniform and consistent evaluation of modeled data in the
process of drug development.