A treatment method and apparatus for providing a substance to be absorbed onto a surface of a patient's skin, includes applying the substance onto the surface of the patient's skin by way of a probe head that provides, at the same time: i) bursts of electrical pulses to the skin surface, and ii) vibrations to the skin surface. The vibrations are applied to the skin surface at substantially a same frequency rate, a first harmonic of the same frequency rate, and/or a second harmonic of the same frequency rate, as a burst rate of electrical pulses being applied to the skin surface.