The present invention provides methods and systems for accessing a database with a database-enabled messaging facility. An application on a front-end server may access a database located on a back-end server via the database-enabled messaging facility. In general, the database-enabled messaging facility receives a message containing a database request from the front-end server, parses the message to extract the database request, submits the database request to the database, receives results from the database request and sends a message containing results from the database request to the front-end server. For some embodiments, the messaging facility may optimize-accessing the database by changing database requests-prior to submitting them to the database. For example, the messaging facility may reorder database requests, delete redundant database requests, or combine database requests to minimize a total number of database accesses.