An improved rotary confocal fluorescence scanner capable of detecting
analytes separated on over a 1,000 capillaries simultaneously. This
system uses a confocal microscope objective and mirror assembly that
rotates inside a vertical ring of capillaries to provide rapid and
efficient excitation and detection of fluorescently labeled fragments
separated within a cylindrical capillary array. Use of automated
procedures to load and run all capillaries permits one to read more than
350,000 base pairs of raw sequence data per hour.