The invention describes novel methods for treating and preventing dementia
caused by vascular diseases; dementia associated with Parkinson's
disease; Lewy Body dementia; AIDS dementia; mild cognitive impairments;
age-associated memory impairments; cognitive impairments and/or dementia
associated with neurologic and/or psychiatric conditions, including
epilepsy, brain tumors, brain lesions, multiple sclerosis, Down's
syndrome, Rett's syndrome, progressive supranuclear palsy, frontal lobe
syndrome, and schizophrenia and related psychiatric disorders; cognitive
impairments caused by traumatic brain injury, post coronary artery
by-pass graft surgery, electroconvulsive shock therapy, and chemotherapy,
administering a therapeutically effective amount of at least one of the
cholinesterase inhibitor compounds described herein. The invention also
describes novel methods for treating and preventing delirium, Tourette's
syndrome, myasthenia gravis, attention deficit hyperactivity disorder,
autism, dyslexia, mania, depression, apathy, and myopathy associated with
diabetes by administering a therapeutically effective amount of at least
one of the cholinesterase inhibitor compounds described herein. The
invention also describes novel methods for delaying the onset of
Alzheimer's disease, for enhancing cognitive functions, for treating and
preventing sleep apnea, for alleviating tobacco withdrawal syndrome, and
for treating the dysfunctions of Huntington's Disease by administering a
therapeutically effective amount of at least one of the cholinesterase
inhibitor compounds described herein. A preferred cholinesterase
inhibitor for use in the methods of the invention is donepezil
hydrochloride or ARICEPT.RTM.. The invention also provides orally
administrable liquid dosage formulations comprising cholinesterase
inhibitor compounds, such as ARICEPT.RTM..