A system for providing an interface between a launch vehicle and a payload of the launch vehicle includes payload integration points of the launch vehicle that remain unchanged relative to different payload configurations, such that a payload is configurable apart from the launch vehicle. The system makes it possible to de-couple payload installation and launch vehicle turnaround operations. Payloads can be configured off-line from launch vehicle processing, thus making it possible to accommodate unique payloads while reducing wear and tear on the launch vehicle.