A monoclonal antibody to a consensus peptide of the formula:
VEKKNITVTASVDPTIDLLQADGSALPSAVALTYSPA (SEQ ID NO. 1) is described. The
monoclonal antibody of the invention binds exclusively to the sequence
SAVALTYS (SEQ ID NO. 2) and has use as a diagnostic and for prophylaxis
against illness arising from E. coli which produce the CS4-CFA/I family
of proteins and for treatment of disease arising therefrom.