The present invention provides methods to reduce or eliminate .alpha.-mannosidase resistant glycans on glycoproteins in yeast. The reduction or elimination of .alpha.-mannosidase resistant glycans on glycoproteins results from the disruption of the newly isolated P. pastoris AMR2 gene encoding .beta.1,2-mannosyltransferase. The present invention also discloses novel genes, polypeptides, antibodies, vectors and host cells relating to .alpha.-mannosidase resistance on glycans.

 
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< Simplified eukaryotic nitrate reductase

< Non-crystalline cellulose and production thereof

> Polypeptides having oxaloacetate hydrolase activity and nucleic acids encoding same

> Process for manufacture of nematode-extracted anticoagulant protein (NAP)

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