It is intended to provide an antibody specific to HbA1c,
antibody-producing cells capable of supplying the antibody in a stable
state in the future, and a method of constructing the antibody-producing
cells without any probability factors, and a method which comprises
fusing mouse spleen cells, which have been sensitized with an immunogen
composed of a compound containing the following structural formula (I)
and a binding protein, with a myeloma-origin cell line, obtaining
monoclonal antibody-producing cells by cloning, and then purifying and
acquiring the monoclonal antibody produced by these cells into the
culture supernatant ##STR00001##