Methods for treating FSH related conditions, such as prostatic
intraepithelial neoplasia, pedophilia, infertility, or vaginal bleeding,
with GnRH antagonists are disclosed. The methods of the invention
generally feature administering to a subject a GnRH antagonist suitable
for in vivo administration and able to reduce both plasma FSH and LH
levels in a subject, in an amount or in a formulation effective to reduce
plasma FSH levels in the subject to a symptom alleviating level. In vitro
fertilization and male contraceptive methods are also provided.