The present patent describes a biocompatible composite made of a first
fibrous layer attached to a three-dimensional inter-connected open cell
porous foams that have a gradient in composition and/or microstructure
through one or more directions. These composites can be made from blends
of absorbable and biocompatible polymers. These biocompatible composites
are particularly well suited to tissue engineering applications and can
be designed to mimic tissue transition or interface zones.