Printing machine with a machine frame (10) and at least two cylinders (16, 20) which cooperate during printing, and which are mounted in a framing (12, 14; 24) formed by the machine frame (10). The framing (12, 14; 24) includes a material which has, at least in a direction transverse to the axes of rotation on the cylinders (16, 20), a linear thermal expansion coefficient that is less than 2.times.10.sup.-6 K-.sup.1. The material can be a composite material, particularly a carbon fiber reinforced plastic.