A fuel cell system has an improved connector assembly to provide for the quick connection of a fuel cartridge and the fuel cell. Two leak resistant connector members with an easy to engage coupling mechanism that stably grips the two connector members to provide for flow between the members. The first connector member is adapted to engage the second connector member to form a unitary structure, which can establish fluid communication between the connector members. Generally, both the first connector member and the second connector member comprise a fluid flow path that can be each sealed/unsealed by a poppet valve or other suitable valve members. In some embodiments, the connector members can be engaged/disengaged by rotating an element of the coupling mechanism. The connector assemblies can be particularly useful for the connection of a fuel cell with a fuel cartridge.