A method of non-invasively measuring the presence, absence, or concentration of one or more analytes in a tissue of a subject includes exposing at least a portion of a tissue of the subject to electromagnetic radiation; obtaining a measurement of electromagnetic radiation from the tissue; and determining the presence, absence, or concentration of one or more analytes by determining a radiation signature of the electromagnetic radiation; correlating the radiation signature of the electromagnetic radiation with at least one of concentration, presence, and absence of one or more analytes by utilizing a mathematic transformation such as a transformation based on a 1.sup.st or higher derivative of the measurement to determine the presence, absence, or concentration of one or more analytes in the subject.

 
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< Solid preparation comprising an insulin sensitizer, an insulin secretagogue and a polyoxyethylene sorbitan fatty acid ester

> Tissue augmentation device

> Synchronization and calibration of clocks for a medical device and calibrated clock

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