A multi-layer and multi-direction radial fan device is disclosed, comprising an upper cover, a tower fan body, a cavity partition and a lower cover. The tower fan body is located in the upper cover, and the tower fan body comprises a first fan layer and a second fan layer. The cavity partition is located under the upper cover, wherein the cavity partition comprises an opening, and the tower fan body extends through the opening so as to make the first fan layer between the upper cover and the cavity partition. The lower cover is located under the cavity partition, wherein the lower cover comprises an opening to expose the bottom surface of the second fan layer, and the second fan layer is located between the cavity partition and the lower cover.